Orexins are neuro-modulatory peptides involved in the control of diverse physiological functions through interaction with two receptors, orexin-1 (OX1R) and orexin-2 Collections (OX2R).Recent evidence in pre-clinical models points toward a putative dichotomic role of the two receptors, with OX2R predominantly involved in the regulation of the sleep
An exploratory, randomized, parallel-group, open-label, relative bioavailability study with an additional two-period crossover food-effect study exploring the pharmacokinetics of two novel formulations of pexmetinib (ARRY-614)
Lance A Wollenberg,1 Donald T Corson,2,3 Courtney A Nugent,1 Farran L Peterson,1 Ann M Ptaszynski,1 Alisha Arrigo,2,3 Coralee G Mannila,2,3 Kevin S Litwiler,1 Stacie J Bell1,4 1Array BioPharma, Boulder, 2Array BioPharma, Longmont, CO, 3Avista Pharma Solutions, Longmont, CO, 4Mallinckrodt Pharmaceuticals, Ellicott City, MD, USA Background: Pexmetini
A motor imagery EEG signal optimized processing algorithm
Feature extraction and classification is a difficult area in motor imagery electroencephalogram (EEG) signal processing.In order to improve the classification accuracy of EEG signals, both a feature extraction method based on the combination of LMD-CSP and a classification algorithm based on the fusion of PSO-SVM are proposed.Firstly, the extended
AUTOMATED CO-REGISTRATION OF INTRA-EPOCH AND INTER-EPOCH SERIES OF MULTISPECTRAL UAV IMAGES FOR CROP MONITORING
The application of UAV-based aerial imagery has advanced exponentially in the past two decades.This can be attributed to UAV operational flexibility, ultra-high spatial resolution, inexpensiveness, and UAV-based sensors enhancement.Nonetheless, the application of multitemporal series of multispectral UAV imagery still suffers significant misregistr